98% Purity Food Additives 4-Aminobutyric acid CAS 56-12-2

98% Purity Food Additives 4-Aminobutyric acid CAS 56-12-2

 

Product Name: 4-Aminobutyric acid
Synonyms: 4-AMINOBUTANOIC ACID;4-AMINOBUTYRIC ACID;4-AMINO-N-BUTYRIC ACID;ALPHA-AMINOBUTANOIC ACID;AMINOBUTYRIC ACID, 4-;AMINOBUTYRIC-4 ACID;AURORA KA-1053;H-4-AMINOBUTYRIC ACID
CAS: 56-12-2
MF: C4H9NO2
MW: 103.12
EINECS: 200-258-6
Product Categories: Pharmaceutical Raw Materials;Starting Raw Materials & Intermediates;Amino Acids;Biochemistry;non-Proteinorganic Amino Acids;omega-Aminocarboxylic Acids;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Amino Acids;Food Additives;Peptide;GABA/Glycine receptor;GABA;Aliphatics;Amino Acids & Derivatives;API
Melting point 195 °C (dec.)(lit.)
FEMA 4288
Storage temp. Store at RT.
Chemical Properties White microcrystalline powder
Usage An important inhibitory neurotransmitter. The foods contain γ-aminobutyric acid (GABA) at an amount that shows immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity.
Usage antihypertensive

Pharmaceuticals Personal Care Products Antibiotics CAS 7081-44-9 Cloxacillin Sodium

 

Product Name: Cloxacillin sodium
Synonyms: bactopen;brl-1621sodiumsaltmonohydrate;cloxacillinsodiummonohydrate;orbeninsodiumhydrate;prostaphlin-amonohydrate;sodiumcloxacillinmonohydrate;staphobristol-250;thyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-,sodiumsalt,monohydrate
CAS: 7081-44-9
MF: C19H19ClN3NaO6S
MW: 475.88
EINECS: 211-390-9
Product Categories: Antibiotics for Research and Experimental Use;beta-Lactams (Antibiotics for Research and Experimental Use);Biochemistry;Interferes with Cell Wall SynthesisEPA;A – KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Mechanism of Action;NeatsAntibiotics;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity;1694 Pharmaceuticals&Personal Care Products;BactericidalAntibiotics;beta-Lactam StructureAlphabetic;Chemical Structure;CI – CLEPA;Principle;Antibiotics;C;Neats;Peptide Synthesis/Antibiotics;TEGOPEN
Storage temp. : 2-8°C
Merck : 13,2444
Appearance : White powders
Usage : antibacterial .

Non Steroid Anti-inflammatory Analgesic Indometacin CAS 53-86-1

Non Steroid Anti-inflammatory Analgesic Indometacin CAS 53-86-1

 

Quick Details for Indometacin

Product Name: Indometacin
Synonyms: AURORA KA-6542;INDOCIN;INDOMETACIN;INDOMETACINE;INDOMETHACIN;INDOMETHACINE;LABOTEST-BB LT00244830;1-(P-CHLOROBENZYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID
CAS: 53-86-1
MF: C19H16ClNO4
MW: 357.79
EINECS: 200-186-5
Product Categories: PHARMACEUTICALS;Active Pharmaceutical Ingredients;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Lipid signaling;INDOCIN;Other APIs;Pharmaceutical raw chemicals
Melting point : 155-162 °C
Storage temp. : Store at RT
Solubility ethanol: 50 mg/mL, clear, yellow-green
Chemical Properties : Crystalline Solid
Usage : Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD .
Usage : antiinflammatory, antipyretic, analgesic .
1.The product is anti-inflammatory, and antipyretic effect is obvious, mainly is used for salicylates to tolerance or the effect is not significant rheumatism and arthritis, ankylosing light spondylitis, osteoarthritis.
2.Non steroid anti-inflammatory analgesic .

 

Anti-inflammatory analgesic

Indomethacin is a kind of stronger corticoid anti-inflammatory and antipyretic and analgesic, by inhibiting cyclooxygenase reducing the synthesis of prostaglandin (PG), to prevent the formation of the nere impulses, inflammation tissue inhibiting inflammatory reaction, including inhibition of leukocyte chemotaxis and lysosomal enzyme release, etc., and produce antipyretic, analgesic and anti-inflammatory effects. Indomethacin anti-inflammatory, antipyretic effect is very strong, its anti-inflammatory effect is better than bute, 84 times better than hydrocortisone, and sugar cortical hormone, used in combination with aspirin, bute, can reduce their dosage, toxic and side effects, improve curative effect; Second is antipyretic effect, 10 times than amidopyrine ;its analgesic action is weak , only to the inflammatory pain has obvious analgesic effect, but the effect is good for inflammatory pain than Baotai loose, analgin and salicylic acid. Clinical is mainly used for the salicylic acid, drugs are less tolerance or curative effect is not obvious in the acute and chronic rheumatic or rheumatoid arthritis, ankylosing spondylitis, slippery bursa phlogistic, tenosynovitis, articular capsulitis, osteoarthritis and acute gout and cancerous pain, etc.In recent years, the researchers try to use indomethacin biliary colic, dysmenorrhea, migraine, glomerulonephritis, polyuria, salmonella gastroenteritis, orthostatic hypotension, bart syndrome and so on, all have good curative effect.It can also be used to treat eye pigment meningitis, keratitis, scleritis, glaucoma and fever caused by cancer or other difficult to control the fever. Dermatologist for lupus erythematosus (sle), white plug syndrome, scleroderma, nodular erythema, herpes zoster, joint type of psoriasis, etc. photosensitive dermatitis induced by topical treatment of eczema, allergic dermatitis, and local pain.

 

Usage and dosage

1.Anti-rheumatism: adult dosage: oral: early quantity from 25 to 50 mg each time, 2 ~ 4 times a day, immediately take at food service or after a meal. Such as good tolerance, the daily dosage can be increased from 25 to 50 mg per week, the most mount should not be more than 200 mg a day. Arthritis patients such as persistent pain at night or morning stiffness, can give quantity of 100 mg in bed all day.

2. Resistance to gout: oral: At the beginning quantity is 100 mg once, then 50 mg, three times a day, until the pain relief, and then gradually reduced as soon as possible, until the drug withdrawal.

3. Antifebrile: adult dosage: oral: 25 ~ 50 mg each time, 3 ~ 4 times daily.Rectal drug delivery: every time 50 mg, 50 to 100 mg per day. Pediatric dosage: oral: 0.5 ~ 1 mg/kg each time, 3 times a day.

Pharmaceuticals Personal Care Products Antibiotics CAS 7081-44-9 Cloxacillin Sodium

Pharmaceuticals Personal Care Products Antibiotics CAS 7081-44-9 Cloxacillin Sodium

 

Product Name: Cloxacillin sodium
Synonyms: bactopen;brl-1621sodiumsaltmonohydrate;cloxacillinsodiummonohydrate;orbeninsodiumhydrate;prostaphlin-amonohydrate;sodiumcloxacillinmonohydrate;staphobristol-250;thyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-,sodiumsalt,monohydrate
CAS: 7081-44-9
MF: C19H19ClN3NaO6S
MW: 475.88
EINECS: 211-390-9
Product Categories: Antibiotics for Research and Experimental Use;beta-Lactams (Antibiotics for Research and Experimental Use);Biochemistry;Interferes with Cell Wall SynthesisEPA;A – KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Mechanism of Action;NeatsAntibiotics;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity;1694 Pharmaceuticals&Personal Care Products;BactericidalAntibiotics;beta-Lactam StructureAlphabetic;Chemical Structure;CI – CLEPA;Principle;Antibiotics;C;Neats;Peptide Synthesis/Antibiotics;TEGOPEN
Storage temp. : 2-8°C
Merck : 13,2444
Appearance : White powders
Usage : antibacterial .

Vitamin Ingredients Food Grade Thiamine hydrochloride CAS 67-03-8

Vitamin Ingredients Food Grade Thiamine hydrochloride CAS 67-03-8

 

Product Name: Thiamine hydrochloride
Synonyms: VIT B1;VITAMIN B1 HCL;VITAMIN B1 HYDROCHLORIDE;TIMTEC-BB SBB001377;THIAMINE;THIAMINE CHLORIDE HYDROCHLORIDE;THIAMINE HCL;THIAMINE HYDROCHLORIDE
CAS: 67-03-8
MF: C12H18Cl2N4OS
MW: 337.27
EINECS: 200-641-8
Product Categories: Biochemistry;Vitamins;Vitamins and derivatives;Vitamin Ingredients;Miscellaneous Compounds;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Vitamin B1;vitamin;Nutritional supplement.;Inhibitors
Melting point : 250 °C (dec.)(lit.)
FEMA : 3322
Storage temp. : 2-8°C
Chemical Properties : White crystalline powder
Usage : Vitamin
Usage : Thiamine is a essential nutrient required for carbohydrate metabolism; also involved in nerve function. Biosynthesized by microorganisms and plants. Dietary sources include whole grains, meat products , vegetables, milk, legumes and fruit. Also present in rice husks and yeast. Converted in vivo to Thiamine diphosphate, a coenzyme in the decarboxylation of α-keto acids. Chronic deficiency may lead t o neurological impairment, bariberi, Wernicke-Korsakoff syndrome.

Local Antiseptic Pharmaceutical Intermediates Adenine CAS 73-24-5

Local Antiseptic Pharmaceutical Intermediates Adenine CAS 73-24-5

 

Product Name: Adenine
Synonyms: 1,6-dihydro-6-imino-9h-purin;1H-Purine, 6-amino-;1h-purine,6-amino;1H-Purine-6-amine;3,6-Dihydro-6-iminopurine;6-Amino-3H-purine;6-Amino-7H-purine;6-Amino-9H-purine
CAS: 73-24-5
MF: C5H5N5
MW: 135.13
EINECS: 200-796-1
Product Categories: PYRIMIDINE;Pharmaceutical Intermediates;Purines;PLANT GROWTH REGULATOR;Nucleobases and their analogs;Plant Growth Regulators;Biochemistry;Cytokinins;Nucleosides, Nucleotides & Related Reagents;Nutritional Supplements;Nucleic acids;Nucleic acid purification;Vitamin Ingredients;Other Products;Amines;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;MONACRIN;nucleoside;Inhibitors;vitamin series;Pyridines ,Halogenated Heterocycles
Melting point : >360 °C(lit.)
Fp : 220°C
Storage temp. : Store at RT.
Chemical Properties : White to almost white crystalline powder
Usage local antiseptic
Usage Vitamin B4
Usage Widespread throughout animal and plant tissues combined with niacinamide, d-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coa laninedehydrase. It is used in microbial determination of niacin; in research on heredity, virus diseases, and cancer.
Usage enteric coating .

Antibacterial Pharmaceutical Raw Materials Amikacin Disulfate Salt CAS 39831-55-5

Antibacterial Pharmaceutical Raw Materials Amikacin Disulfate Salt CAS 39831-55-5

 

Quick Details for Amikacin disulfate salt

Product Name: Amikacin disulfate salt
Synonyms: AMIKACIN SULPHATE;AMIKACIN DISULFATE;AMIKACIN DISULFATE SALT;AMIKACIN SULFATE;(s)-ysulfate(1:2)(salt);antibioticbb-k8sulfate;y-alpha-d-glucopyranosyl-(1-4))-n(sup1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deox;amikacin bis(sulphate)
CAS: 39831-55-5
MF: C22H47N5O21S2
MW: 781.76
EINECS: 254-648-6
Product Categories: Active Pharmaceutical Ingredients;Amines;Intermediates & Fine Chemicals;Oligosaccharides;Pharmaceuticals;AMIKIN;Antibiotics;Inhibitors
Melting point : 220-230 C
Storage temp. : 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Chemical Properties : White Solid
Usage : Analgesic
Usage : Semisynthetic aminoglycoside antibiotic derived from Kanamycin A . Antibacterial .

 

Amikacin disulfate salt Description

Amikacin is an antibiotic used for a number of bacterial infections. This includes joint infections, intraabdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis. It is used either by injection into a vein or muscle.

Common side effects include hearing loss, balance problems, and kidney problems. Other side effects include paralysis resulting in the inability to breathe. If used during pregnancy it may cause permanent deafness in the baby. Amikacin is in the aminoglycoside family of medications. It works by blocking the function of the bacteria’s 30S ribosomal subunit, making it unable to make protein.

Amikacin was patented in 1971 and came into commercial use in 1976. It is on the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is 13.80 to 130.50 USD for a month. In the United States a typical course of treatment costs 25 to 50 USD. It is made from kanamycin .

 

Amikacin disulfate salt Medical uses

Amikacin is most often used for treating severe, hospital-acquired infections with multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter. Serratia marcescens and Providencia stuartii are also included in the spectrum. Amikacin can also be used to treat non-tubercular mycobacterial infections and tuberculosis (if caused by sensitive strains) when first-line drugs fail to control the infection .

Amikacin may be combined with a beta-lactam antibiotic for empiric therapy for people with neutropenia and fever .

Liposomal amikacin for inhalation is currently in late stage clinical trials for the treatment of respiratory diseases, such as cystic fibrosis, Pseudomonas aeruginosa, non-tubercular mycobacterial infections and bronchiectasis .