IDRA 21

Nootropics Improve Memory API Ampakine CAS 22503-72-6 IDRA 21

 

Product Name: IDRA 21
Synonyms: IDRA 21;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE S,S-DIOXIDE;IDRA 21,98%;2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-Methyl-, 1,1-dioxide;AMPAKINE
CAS: 22503-72-6
MF: C8H9ClN2O2S
MW: 232.69
Storage temp.: Store at RT
Chemical Properties: white to off-white crystalline powder
Purity : 99%
Package: 1kg/25kg/package
Uses: IDRA-21 inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide.

 

AMPAKINE Description :

The goal is to treat diseases such as stroke in the brain, but to extend the benefits of memory and the brain.
Ampakine shows significant improvements in memory, attention, speed of response and problem solving in clinical trials. At the same time, it is estimated that the drug for sudden sleep disorders, inverted time difference, attention deficit hyperactivity disorder and other issues have a better solution .

Armodafinil

Antidepressant Nootropics Analeptic Pharmaceutical CAS 112111-43-0 Armodafinil for Spontaneous Narcolepsy

 

Product Name: Armodafinil
Synonyms:2-[(R)-(Diphenylmethyl)sulfinyl]-acetamide
CAS: 112111-43-0
MF:C15H15NO2S
MW:273.354
Product Categories:Chiral Reagents;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals
Melting point: 156-158℃
Density: 1.283
Chemical Properties: White Solid
Purity : 99%
Package : 1kg/25kg/package
Uses: Used for treatment of excessive sleepiness, a1-adrenoceptor agonist .
Uses: Analeptic. Has the role of arousal and cognitive improvement . For the treatment of spontaneous narcolepsy and narcolepsy drug .

 

Armodafinil Description

Armodafinil is the enantiopure compound of the eugeroic modafinil (Provigil).It consists of only the (R)-(−)-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc.and was approved by the U.S. Food and Drug Administration (FDA) in June 2007.

Because armodafinil has a longer half-life than modafinil does, it may be more effective at improving wakefulness in patients with excessive daytime sleepiness.

 

Medical uses

Armodafinil is currently FDA-approved to treat excessive daytime sleepiness associated with obstructive sleep apnea, narcolepsy, and shift work disorder. It is commonly used off-label to treat attention deficit hyperactivity disorder, chronic fatigue syndrome, and major depressive disorder. It has been shown to improve vigilance in air traffic controllers.

Sleep disorders

Armodafinil is approved by the U.S. FDA for the treatment of narcolepsy and shift work sleep disorder, and as an adjuvant therapy for obstructive sleep apnea.For narcolepsy and obstructive sleep apnea, armodafinil is taken as a once daily 150 mg or 250 mg dose in the morning. For shift work sleep disorder, 150 mg of armodafinil are taken one hour prior to starting work. Slow dose titration is needed to mitigate some side effects.

Schizophrenia

In June, 2010, it was revealed that a phase II study of armodafinil as an adjunctive therapy in adults with schizophrenia had failed to meet the primary endpoints, and the clinical program was subsequently terminated.However, a study published later that year showed that schizophrenic patients treated with armodafinil showed fewer of the negative symptoms of schizophrenia.

Piracetam

Nootropic and Antinauseant Powders Piracetam CAS 7491-74-9

 

Product Name : Piracetam
Synonyms: IFLAB-BB F1918-0022;2-(2-OXOPYRROLIDIN-1-YL)ACETAMIDE;2-(2-OXOPYRROLIDINO)ACETAMIDE;2-OXO-1-PYRROLIDINEACETAMIDE;N-CARBAMOYLMETHYL-2-PYRROLIDINONE;PIRACETAM;1-Acetamido-2-pyrrolidinone;1-Pyrrolidineacetamide, 2-oxo-
CAS: 7491-74-9
MF: C6H10N2O2
MW: 142.16
EINECS: 231-312-7
ProductCategories:Miscellaneous;API’s;Amines;Heterocycles;Intermediates
& Fine Chemicals;Pharmaceuticals;Nootropic;Smart drug;NORZETAM;
Cardiovascular APIs
Melting point : 151-152,5 C
Storage temp. : Store at RT
Appearance : White powders
Purity : 99%
Package : 25kg/drum
Uses : Nootropic and Antinauseant .Piracetam is the parent compound of the racetam class of nootropic supplements. When supplemented , it provides a mild boost to brain function .

 

Things to Note

1.Piracetam is water-soluble, and does not need to be taken with food .
2.Many studies note a high inter-individual variability .
3.It is (anecdotally) reported to be non-stimulatory and non-sedative .

 

Piracetam Description

Piracetam is the prototype for racetam supplements, which are a group of synthetic supplements intended to provide a cognitive boost .

Piracetam has a history of being used to treat cognitive impairment. According to a meta-analysis on human studies, piracetam improves general cognition when supplemented by people in a state of cognitive decline, such as the kind that comes with aging. Though piracetam may be a useful supplement for improving longevity, it offers limited benefits for healthy people .

Healthy people supplementing piracetam do experience little to no cognitive benefit. Though piracetam supplementation in healthy people is understudied, preliminary evidence suggests that piracetam is most effective for older people. Piracetam supplementation has also been found to reduce the chances of a breath-holding spell in children .

Piracetam enhances cellular membrane fluidity. This mechanism explains why piracetam is able to improve cognition, particularly in elderly people .

Piracetam is as effective as aspirin when it comes to preventing blood clotting, which makes it a useful supplemental intervention after cardiovascular trauma .

 

How to Take
Recommended dosage, active amounts, other details

The standard piracetam dose for children is between 40-100mg per kilogram of bodyweight. This dose is intended for the treatment of breath-holding spells, though it has also been used for children with dyslexia. The lower end of the range (40-50mg/kg) is used most often.

The standard piracetam dose for adults is between 1,200-4,800mg a day. The largest effective dose is 1,600mg, taken three times a day for a total of 4,800mg.

Tianeptine Sulfate

Nootropic Pharmaceutical Powders Tianeptine Sulfate CAS 1224690-84-9

 

Product Name: Tianeptine sulfate
Synonyms:tianeptine sulfate;Tianeptine hemisulfate monohydrate (THM)
CAS: 1224690-84-9
MF: 2(C21H25ClN2O4S).H2SO4.2(H2O)
Appearance : White powders
Purity : 99%
Package : 1kg/foil bag
Usage : Nootropic and Antinauseant .

 

Tianeptine Sulfate, also called tianeptine hemisulfate monohydrate, is an improved version of the tianeptine sodium salt form. It is non-hygroscopic, easier to handle, goes down easier, and lasts twice as long. It has all of the same benefits as Tianeptine Sodium, only the sulfate form has a half-life of 5-6 hours, so it lasts twice as long as tianeptine sodium. Because of this, researchers will need 2-3 times the amount of sulfate to achieve the desired results that they have come to love from sodium. Sulfate is also less volatile in both taste and viscosity. Tianeptine Sulfate is available in 5, 10, and 20 gram glass vials.

 

Usage :

Large Dosage
Due to a more controlled release, larger doses may be required to reach the same peak plasma levels as with Tianeptine Sodium.

Molar Mass
Furthermore, considering the molar masses of the two (98g/mol Sulfate vs 22g/mol Sodium) there will need to be more Tianeptine Sulfate for the same amount to be present in the body.

 

Tianeptine Sulfate – Duration of Action

When compared to Tianeptine Sodium, the Sulfate form is expected to last up to three times longer .

Tianeptine Sulfate is absorbed by the body at a slower rate, meaning it takes longer to reach peak effect – extending it’s duration of action.

Tianeptine Sulfate is excreted much more slowly than Tianeptine Sodium, meaning it remains active within the body for a longer duration.

 

Tianeptine Sulfate – Improved Properties

Hygroscopicity

One of the main downsides to Tianepine Sodium is its ability to clump after exposure to normal conditions.

Tianeptine Sulfate does not absorb moisture from the air, and remains as a powder – making it much easier to work with.

Stability

Tianeptine Sodium is not stable in atmospheric moisture, and is very light sensitive, degrading quickly when exposed.

Tianeptine Sulfate is much more stable, with much less light degradation .

Taste

The taste of Tianeptine Sodium has been described as “bitter” and reportedly “tastes like death”.

Tianeptins Sulfate, on the other hand, has very little taste at all.