Antifungal Pharmaceutical Raw Materials Levamisole hydrochloride CAS 16595-80-5

Antifungal Pharmaceutical Raw Materials Levamisole hydrochloride CAS 16595-80-5

 

Product Name: Levamisole hydrochloride
Synonyms: 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(s)-imidazo(;1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,l-(-)-imidazo(;1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-Imidazo[2;citarinl;decaris;Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-;kw-2-le-t;L-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-6]-thiazole
CAS: 16595-80-5
MF: C11H13ClN2S
MW: 240.75
EINECS: 240-654-6
Product Categories: API;Asymmetric Synthesis;Synthetic Organic Chemistry;Antibiotic Explorer;Veterinaries;Protein Phosphatase;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Pharma;Pharmaceutical intermediate;REZIFILM;Other APIs
Melting point : 266-267 °C(lit.)
Alpha : -128 º (c=5, H2O)
Refractive index : -126 ° (C=1, H2O)
Storage temp. : 0-6°C
Chemical Properties White to almost white crystalline powder
Usage Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.
Usage antifungal .

Antibiotics Antibacerial Pharmaceutical Raw Materials Rifampicin CAS 13292-46-1

Antibiotics Antibacerial Pharmaceutical Raw Materials Rifampicin CAS 13292-46-1

 

Product Name: Rifampicin
Synonyms: ,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2-h)-dione,5,6;3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-((4-methyl-1-piperazinyl)iminomethyl)rifamycinsv;8-(((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv;8-(4-Methylpiperazinyliminomethyl)rifamycinSV;8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins;8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycinSV
CAS: 13292-46-1
MF: C43H58N4O12
MW: 822.94
EINECS: 236-312-0
Product Categories: Antibiotics;Organics;Antitubercular;Antibiotics for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Peptide Synthesis/Antibiotics;Chiral Reagents;Isotope Labelled Compounds;RIFADIN;antibiotic
Melting point : 183°C (dec.)
Storage temp. : 2-8°C
Chemical Properties : Red to Orange Crystalline Solid
Usage : Semisynthetic antibiotic. Antibacerial (tuberculostatic) .
Usage : antibacterial (tuberculostatic) .

 

Rifampicin Description

Rifampicin, also known as rifampin, is an antibiotic used to treat several types of bacterial infections. This includes tuberculosis, leprosy, and Legionnaire’s disease. It is almost always used along with other antibiotics, except when given to prevent Haemophilus influenzae type b and meningococcal disease in people who have been exposed to those bacteria. Before treating a person for a long period of time, measurements of liver enzymes and blood counts are recommended. Rifampicin may be given either by mouth or intravenously .

Dermatologist Broad-spectrum Antifungal Drugs Terbinafine Hydrochloride CAS 78628-80-5

Dermatologist Broad-spectrum Antifungal Drugs Terbinafine Hydrochloride CAS 78628-80-5

 

Product Name: Terbinafine Hydrochloride
Synonyms: (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethylaminehydroc;lamosil;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmonohydrochloride;TERBINAFINE HCL;N-[(2E)-6,6-DIMETHYL-2-HEPTEN-4-YNYL]-N-METHYL-1-NAPHTHALENEMETHANAMINE;TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE;(e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine monohydrochloride
CAS: 78628-80-5
MF: C21H26ClN
MW: 327.89
EINECS: 245-385-8
Product Categories: Antifungal;APIs;Acetylenes;Antifungals for Research and Experimental Use;Biochemistry;Functionalized Acetylenes;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Terbinafine;LAMISIL
Melting point : 204-208°C
Storage temp. : -20°C Freezer
Chemical Properties : Crystalline Powder
Usage : An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal .

 

Dermatologist Broad-spectrum Antifungal Drugs

Terbinafine hydrochloride is a kind of broad-spectrum dermatologist allyl amine antifungal drugs. It is developed by Swiss Novartis in the 1980 s, and appeared in the market of UK for the first time in 1991. Approved by FDA of the United States for OTC drugs in 1996, and appeared in the market of the United States in the same year. At present, the drug is been sold in more than 90 countries of the word. It can specificity trouble the late biological decomposition of fungus sterol, selectively inhibit the activity of fungal squalene ring oxidase, and inhibit the squalene epoxidation in the formation of ungal cell membrane, thus to kill or inhibit the active of the fungus. Suitable for treatment of candidiasis skin, such as tinea manuum, tinea, tinea, ringworm of the body, tinea versicolor, it is also the best medicine for the treatment of onychomycosis.

Terbinafine hydrochloride entered the the first batch of country announced OTC directory in 2000. This product belongs to antifungal drugs. It has strong effect on shallow fungal infection, and can cure most of the fungal skin diseases through external use.

 

Terbinafine Hydrochloride Usage and Dosage

Local external use: apply adequate amount to the affected area and its surrounding, 1-2 times a day. Ringworm of the body, 2-4 weeks, tinea of feet and hands, tinea versicolor, 4 to 6 weeks.

Oral: 0.25 grams each time for adult, once per day, period of treatment is as follows:

Skin infection treatment: tinea of feet and hands [toe (means) and plantar]: 2 ~ 6 weeks; Ringworm of the body, tinea, 2 ~ 4 weeks.

Skin candidiasis: 2 ~ 4 weeks. normal skin appearance and loss of infection can only be visible in a few weeks for curing.

Hair and scalp infection treatment: tinea capitis: 4 weeks, tinea capitis most happen in children.

Onychomycosis: The most treatment course of patients is 6 weeks to three months. Young patients with normal growth can shorten the treatment course, and less than 3 months of treatment may be enough in addition to the thumb (foot) armour.
In other cases, the treatment is usually 3 months. Some patients, especially whose thumb (toe) infected, may take 6 months or longer. The treatment may take more than 3 months if the nail grew slowly in the first week. In healing of mycology and stopping for a few months after treatment, the continuous improvement of nail appearance then completely normal can be seen, this is because that the healthy tissue growth needs time.

Veterinary Medicine Raw Powders Sulfachloropyridazine sodium CAS 23282-55-5

Veterinary Medicine Raw Powders Sulfachloropyridazine sodium CAS 23282-55-5

 

Product Name: Sulfachloropyridazine sodium
Synonyms: N-(6-CHLORO-3-PYRIDAZINE)-4-AMINOBENZENESULFONAININO SODIUM MONOHYDRATE;SULFACHLOROPYRIDAZINE SODIUM;SULFACHLOROPYRIDAZINE SODIUM H2O;SPDZ;Sodium N-(6-chloropyridazin-3-yl)sulphanilamidate;sulphachlorpyridazine sodium;Sulfachlorpyridazine Sodium SPDZ;SULFACHLOROPYRIDAZINE SODIUM(SPDZ):N-(6-CHLORO-3-PYRIDAZINE)-4-AMINOBENZENESULFONAININO SODIUM MONOHYDRATE
CAS: 23282-55-5
MF: C10H8ClN4NaO2S
MW: 306.7
EINECS: 245-553-0
Product Categories: API;pharmaceutical
Chemical Properties : Light yellow powder
Usage : Sulfachlorpyridazine is an antibacterial compound.

 

Sulfachloropyridazine Sodium Application

Use for livestock anti-inflammatory antibacterial drugs, mainly for chicken E. coli, staphylococcal infection, white crown disease, chicken and typhoid fever and other infectious diseases .

Use to block the synthesis of microbial tetrahydrofolic acid. Has a broad spectrum of antibacterial effect, can resist Gram-positive and Gram-negative bacteria. Oral 1-3 hours of plasma concentration reached the highest value. Sulfonamides. For livestock and poultry (pig, chicken) E. coli and Pasteurella infection.

Use is mainly used for livestock and poultry E. coli and Pasteurella infection .

Anticonvulsant Active Pharmaceutical Ingredients Topiramate CAS 97240-79-4

Anticonvulsant Active Pharmaceutical Ingredients Topiramate CAS 97240-79-4

 

Product Name: Topiramate
Synonyms: 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranossulfamate;MCN 4853;2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-36-D-FRUCTO-PYRANOSE SULFAMATE;2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-B-D-FUCTO-PYRANOSE SULFAMATE;2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose sulfamate;2,3:4,5-BIS-O-(1-METHYLETHYLIDENE)-BETA-D-FUCTOPYRANOSE SULFAMATE;RWJ 17021;RWJ-17021-000
CAS: 97240-79-4
MF: C12H21NO8S
MW: 339.36
EINECS: 200-659-6
Product Categories: Active Pharmaceutical Ingredients;APIs;Health & Beauty;Carbohydrates & Derivatives;Pharmaceuticals;Glutamate receptor;Intermediates & Fine Chemicals;API;TOPAMAX;Pharmaceutical raw materials
Melting point : 125°C
Storage temp. : 2-8°C
Chemical Properties : White-to-Off-White Crystalline Powder
Usage : anticonvulsant, antimigraine, GABA-A agonist, AMP/kinate glutamate receptor antagonist, carbonic anhydrase inhibitor
Usage : Used for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome.
Usage : Used as an anticonvulsant .

 

Topiramate Description

Topiramate (brand name Topamax) is an anticonvulsant (antiepilepsy) drug. In late 2012, topiramate was approved by the United States Food and Drug Administration (FDA) in combination with phentermine for weight loss. The drug had previously been used off-label for this purpose. Topiramate was originally produced by Ortho-McNeil Neurologics and Noramco, Inc., both divisions of the Johnson & Johnson Corporation. This medication was discovered in 1979 by Bruce E. Maryanoff and Joseph F. Gardocki during their research work at McNeil Pharmaceutical.

 

Topiramate Medical uses

Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant. In children, it is indicated for the treatment of Lennox-Gastaut syndrome, a disorder that causes seizures and developmental delay. It is also Food and Drug Administration (FDA) approved for, and most frequently prescribed for, the prevention of migraines. The drug is also used to treat migraines due to the effect it has on the blood vessels in the brain. It has been found to be increasingly effective for migraine sufferers with limited side effects .

Anti-hypertensive Pharmaceutical Raw Materials CAS 88150-42-9 Amlodipine

Anti-hypertensive Pharmaceutical Raw Materials CAS 88150-42-9 Amlodipine

 

Product Name: Amlodipine
Synonyms: 3,5-pyridinedicarboxylicacid,1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor;3-ethyl5-methylester;LOTREL;methyl ethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;AMLODIPINE;AMLODIPINE BASE;Amlodipin;besylate
CAS: 88150-42-9
MF: C26H31ClN2O8S
MW: 567.05
Product Categories: Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Calcium channel;Aromatics;Dihydropyridine;Heterocycles;API;Free Base API;Norvasc
Melting point : 178-179°C
Storage temp. : Keep in room temperature
Water Solubility : 75.3 mg/L
Chemical Properties : White powders
Usage : A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
Usage : anti-hypertensive;calcium channel blocker
Usage : A deuterated dihydropyridine calcium channel blocker.;Application of Labeled APIs: Labeled Amlodipine, intended for use as an internal standard for the quantification of Amlodipine by GC- or LC-mass spectrometry .

 

Amlodipine Description

Amlodipine, sold under the brand name Norvasc among others, is a medication used to treat high blood pressure and coronary artery disease. While calcium channel blockers are not typically recommended in heart failure, amlodipine may be used if other medications are not sufficient for high blood pressure or heart related chest pain. Amlodipine is taken by mouth and has an effect for at least a day .

Common side effects include: swelling, feeling tired, abdominal pain, and nausea. Serious side effects may include low blood pressure or a heart attack. It is unclear if use is safe during pregnancy or breastfeeding. Doses should be decreased in people with liver problems and in elderly individuals. Amlodipine is a long acting calcium channel blocker of the dihydropyridine type. It works partly by increasing the size of arteries .

Antiinflammatory Pharmaceuticals Famotidine CAS 76824-35-6 for Treatment of PUD and GERD

Antiinflammatory Pharmaceuticals Famotidine CAS 76824-35-6 for Treatment of PUD and GERD

 

Quick Details for Famotidine

Product Name: Famotidine
Synonyms: [amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene]s;3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-n-(aminosulfonyl)p;3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)-n(sup2)-sulfamoylp;aminosulfonyl)-;dispronil;famodil;famosan;famoxal
CAS: 76824-35-6
MF: C8H15N7O2S3
MW: 337.45
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API’s;Histamine receptor;Amines;Heterocycles;Sulfur & Selenium Compounds;LODINE;Other APIs
Melting point : 163-164°C
Storage temp. : Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Chemical Properties White Powder
Usage Histamine H2-receptor antagonist. Antiulcerative.
Usage antiinflammatory
Usage For the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD).
Usage Use as an H2-antagonist. An anti-ulcer agent .

 

Famotidine Description

Famotidine, sold under the trade name Pepcid among others is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.

Unlike cimetidine, the first H2 antagonist, famotidine has no effect on the cytochrome P450 enzyme system, and does not appear to interact with other drugs.