Anti-hypertensive Pharmaceutical Raw Materials CAS 88150-42-9 Amlodipine

Anti-hypertensive Pharmaceutical Raw Materials CAS 88150-42-9 Amlodipine

 

Product Name: Amlodipine
Synonyms: 3,5-pyridinedicarboxylicacid,1,4-dihydro-2-((2-aminoethoxy)methyl)-4-(2-chlor;3-ethyl5-methylester;LOTREL;methyl ethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;AMLODIPINE;AMLODIPINE BASE;Amlodipin;besylate
CAS: 88150-42-9
MF: C26H31ClN2O8S
MW: 567.05
Product Categories: Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Calcium channel;Aromatics;Dihydropyridine;Heterocycles;API;Free Base API;Norvasc
Melting point : 178-179°C
Storage temp. : Keep in room temperature
Water Solubility : 75.3 mg/L
Chemical Properties : White powders
Usage : A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
Usage : anti-hypertensive;calcium channel blocker
Usage : A deuterated dihydropyridine calcium channel blocker.;Application of Labeled APIs: Labeled Amlodipine, intended for use as an internal standard for the quantification of Amlodipine by GC- or LC-mass spectrometry .

 

Amlodipine Description

Amlodipine, sold under the brand name Norvasc among others, is a medication used to treat high blood pressure and coronary artery disease. While calcium channel blockers are not typically recommended in heart failure, amlodipine may be used if other medications are not sufficient for high blood pressure or heart related chest pain. Amlodipine is taken by mouth and has an effect for at least a day .

Common side effects include: swelling, feeling tired, abdominal pain, and nausea. Serious side effects may include low blood pressure or a heart attack. It is unclear if use is safe during pregnancy or breastfeeding. Doses should be decreased in people with liver problems and in elderly individuals. Amlodipine is a long acting calcium channel blocker of the dihydropyridine type. It works partly by increasing the size of arteries .

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