Tetracaine Hydrochloride Powder 136-47-0 Topical Anesthetic Drugs Tetracaine HCL For Opthalmology
Quick Details for Tetracaine Hydrochloride
Product Name:Tetracaine Hydrochloride
Other Name:Land Ocain Hydrochloride;Intercain Hydrochloride;Meethobalm Hydrochloride
Appearence:White crystalline powder
Solubility:Tetracaine hydrochloride soluble in water,dissolved in ethanol.
Category:Local anesthetic drug
Usage :Tetracaine hydrochloride local anesthetic than procaine,toxicity is also bigger,can penetrate the mucosa,mainly for mucosal anesthesia.
Tetracaine Hydrochloride Description
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.