Estradiol

Female Hormone Powder Estrogen Steroids Estradiol CAS 50-28-2

 

Quick Details for Estradiol

Product Name : Estradiol
CAS Registry Number : 50-28-2
Einecs No. : 200-023-8
Molecular formula : C18H24O2
Molecular weight : 272.38
Purity : 99%
Grade : Pharmaceutical Grade
Appearance : White crystalline powder
Usage : Estradiol is the major estrogen secreted by the premenopausal ovary .

 

Estradiol Description

Estradiol, or more precisely, 17β-estradiol, is a steroid and estrogen sex hormone, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

Estradiol is a sex hormone that is present in both males and females, and is the most important form of estrogen in humans. In women, it plays a key role in the development and functioning of the reproductive system, as well as in the growth of certain bones. It also governs the distribution of body fat in women and is the main hormone responsible for the fact that women are shorter than men, on average. Both the ovaries and the adrenal glands produce it.

The menstrual cycle in women involves predictable variations in the levels of several hormones, with estradiol being one of them. It is involved in the ovulation process and prepares the inner lining of the uterus for implantation, should the egg be fertilized. Certain tests done on baboons and other primates have indicated that his hormone also plays a continual role in maintaining a pregnancy, helping it to last for the full gestation period.

As a sex hormone, it also triggers many of the developments of the reproductive system that begin in puberty. It is present throughout the reproductive years, and declines during and after menopause. This decline is precisely what causes many of the symptoms of menopause, such as hot flashes and night sweats, vaginal dryness, and the loss of bone mass that may lead to osteoporosis.

 

Estradiol Function and use

It is a kind of estrogen, can promote and regulate the normal development of women’s genitals and secondary. Can cause hyperplasia of mammary gland carcinoma development, but in larger doses, can inhibit pituitary prolactin release, and reduce the secretion of milk. Potent mammalian estrogenic hormone produced by the ovary.

This medication is a female hormone (estrogen). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. This medication may also be used by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure).

 

Usual Adult Dose for Breast Cancer – Palliative:

10 mg orally 3 times a day for at least 3 months. Estrogen therapy for breast cancer should be considered only for palliation in the treatment of metastatic disease in select patients.

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