Antimicrobial Compound Pharmaceutical Raw Materials Thymol CAS 89-83-8
Quick Details for Thymol
Product Name: Thymol
Synonyms: P-CYMEN-3-OL;PHYMOLSULFONPHTHALEIN;TB;S NO 879;THYME CAMPHOR;THYMOL;THYMOL BLUE TS;THYMOL BLUE ETHANOL (50)
Product Categories: Biochemistry;Monocyclic Monoterpenes;Terpenes
Melting point : 48-51 °C(lit.)
Boiling point : 232 °C(lit.)
Density : 0.965 g/mL at 25 °C(lit.)
Chemical Properties : white crystals or powder with a pungent odour
Usage : Thymol is an antimicrobial compound which can increase the efficacy of antibiotics involving drug resistant bacteria. It inhibits growth and lactate production as well as reduces cellular glucose upta ke within the bacteria.
Thymol (also known as 2-isopropyl-5-methylphenol, IPMP) is a natural monoterpene phenol derivative of cymene, C10H14O, isomeric with carvacrol, found in oil of thyme, and extracted from Thymus vulgaris (common thyme) and various other kinds of plants as a white crystalline substance of a pleasant aromatic odor and strong antiseptic properties. Thymol also provides the distinctive, strong flavor of the culinary herb thyme, also produced from T. vulgaris.
Thymol has antimicrobial activity because of its phenolic structure, and has shown antibacterial activity against bacterial strains including Aeromonas hydrophila and Staphylococcus aureus. In addition, thymol demonstrates considerable post antibacterial effect against some microorganisms. This antibacterial activity is caused by inhibiting growth and lactate production, and by decreasing cellular glucose uptake .
Thymol has been used in alcohol solutions and in dusting powders for the treatment of tinea or ringworm infections, and was used in the United States to treat hookworm infections. People of the Middle East continue to use za’atar, a delicacy made with large amounts of Thyme, to reduce and eliminate internal parasites .
It is also used as a preservative in halothane, an anaesthetic, and as an antiseptic in mouthwash. When used to reduce plaque and gingivitis, thymol has been found to be more effective when used in combination with chlorhexidine than when used purely by itself. Thymol is also the active antiseptic ingredient in some toothpastes, such as Euthymol .