Local Anesthetic Agents Bupivacaine Hydrochloride 14252-80-3 Bupivacaine
Quick Details of Bupivacaine hydrochloride
Product name : Bupivacaine hydrochloride
Alias : Bupivocoine HCl; Marcaina; BUPIVACAINE HYDROCHLORIDE ANHYDROUS
EINECS number: 241-917-8
Molecular formula: C18H31ClN2O2
Molecular Weight: 342.9039
Boiling point: 423.4 ° C at 760 mmHg
Flash Point: 209.9 ° C
Vapor Pressure: 2.24E-07mmHg at 25 ° C
Product use: After local anesthesia for surgery and postoperative analges
Bupivacaine hydrochloride Description
Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area.It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal’s epidural space. It is available mixed with a small amount of epinephrine to make it last longer. It typically begins working within 15 minutes and lasts for 2 to 8 hours.
Possible side effects include sleepiness, muscle twitching, ringing in the ears, changes in vision, low blood pressure, and an irregular heart rate. Concerns exist that injecting it into a joint can cause problems with the cartilage. Concentrated bupivacaine is not recommended for epidural freezing. Epidural freezing may also increase the length of labor. It is a local anaesthetic of the amide group.
Bupivacaine was discovered in 1957. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.Bupivacaine is available as a generic medication and is not very expensive .
Clinical Common usage
Bupivacaine hydrochloride is 2-Piperidinecarboxamide, 1-butyl-N-(2, 6-dimethylphenyl)-, monohydrochloride, monohydrate, a white crystalline powder that is freely soluble in 95 percent ethanol, soluble in water, and slightly soluble in chloroform or acetone .
Local or regional anesthesia or analgesia in surgical procedures (including oral surgery), diagnostic and therapeutic procedures, and obstetrical procedures .
Use of the 0.75% solution of bupivacaine hydrochloride not recommended for obstetrical epidural anesthesia.